Diet Induced Hyperleptinemia and Ghrelin Resistance

In this episode of NeuroEndoNow Dr Zane Andrews from Monash University discusses his paper published in Neuroendocrinology on ‘Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice.

Dr Andrews studies how the brain regulates food intake and body weight during different metabolic states and in response to different endocrine environments. His particular interest involves mitochondrial mechanisms regulating neuronal metabolism and neuro-protection. He is an expert on the neuroendocrine actions of ghrelin in the brain.