IDO predicts death in NEN

Prof. Joerg Schefold of the Bern University Hospital, Switzerland talks about his latest publication in Neuroendocrinology – ‘Increased activity of the immunoregulatory enzyme Indoleamine-2,3-dioxygenase (IDO) with consecutive tryptophan depletion predicts death in patients with neuroendocrine neoplasia’. Interview by Dr Julie Ann Lough

Catecholamine metabolism induces mitochondrial DNA deletions and leads to severe adrenal degeneration during aging

Prof. Rudi Wiesner of the University of Cologne, Germany discusses his recent paper ‘Catecholamine metabolism induces mitochondrial DNA deletions and leads to severe adrenal degeneration during aging’, published in Neuroendocrinology. Prof. Wiesner’s group investigate the mechanisms of mitochondrial loss of function and centres around deciphering this process to be able to slow it down and … Read more “Catecholamine metabolism induces mitochondrial DNA deletions and leads to severe adrenal degeneration during aging”