GnRH deficiency disease, Kallman Syndrome, and Hypogonadotropic Hypogonadism

Dr Anna Cariboni from The University of Milan discusses her work on rare GnRH deficiency disease, Kallman Syndrome, and Hypogonadotropic Hypogonadism, using gene knockout studies.  Interview by Dr Julie Ann Lough Oleari R., Lettieri A., Paganoni A., Zanieri L., Cariboni A. (2018). Semaphorin Signaling in GnRH Neurons: From Development to Disease. Neuroendocrinology. DOI:10.1159/000495916

Corticosteroid action in the brain: the potential of selective receptor modulation

Eva Viho, PhD student at Leiden University Medical Centre, talks to NEN about her recent publication “Corticosteroid action in the brain: the potential of selective receptor modulation.” Interview by Dr Julie Ann Lough Viho E.M.G., Buurstede J.C., Mahfouz A., Koorneef L.L., van Weert L.T.C.M., Houtman R., Hunt H.J., Kroon J., Meijer O.C. (2019). Corticosteroid action … Read more “Corticosteroid action in the brain: the potential of selective receptor modulation”

JAK2/STAT5 pathway mediates prolactin-induced apoptosis of lactotropes

Dr Jimena Ferraris of the Karolinska Institute and the University of Buenos Aires talks with NEN about her recently published work in Neuroendocrinology on the identification of signal transduction pathways that may play a role in the pathogenesis of prolactinomas. Interview by Dr. Julie Ann Lough de Dios, N., Orrillo, S.J., Irizarri, M., Theas, M., … Read more “JAK2/STAT5 pathway mediates prolactin-induced apoptosis of lactotropes”

Female sexual receptivity depends upon extra-ovarian estradiol synthesis in marmoset monkeys

Marissa Kraynak of the University of Wisconsin-Madison talks with NEN at ICN 2018 Toronto about ovarian and extra-ovarian estradiol and how they contribute to sexual receptivity regulation in the marmoset monkey. Interview by Dr. Julie Ann Lough

Novel orally active somotostatin analogs for the treatment of acromegaly

Dr Stephen Betz of Crinetics Pharmaceuticals talks with NEN at ICN 2018 Toronto about his research on the development of treatments for acromegaly; a condition where a pituitary adenoma causes growth hormone hypersecretion causing gigantism in children and abnormal growths in adults. Interview by Dr. Julie Ann Lough